Noninvasive imaging has benefited from technical advances that might allow it to play a pivotal role in cardiovascular diagnosis and patient management. Most notably, advanced imaging modalities have great potential for noninvasive characterization of coronary atherosclerosis as well as quantification of myocardial perfusion. In our view three major obstacles prevent us from achieving these aims: relatively high ionizing radiation of imaging, the often undetected inflammation within atherosclerotic plaques, uncertainties about the relevance of reduced myocardial perfusion and a lack of comprehensive evidence-based results. Therefore, we address these issues with teams of experts in the respective field of experimental radiology, clinical studies, statistics, and outcomes research.
In addition to working on advancing cardiovascular imaging, Marc Dewey’s is focused on implementing a structured graduate program for MDs at Charité. This will allow bringing new process quality to medical dissertations and ensure research integrity and game-changing experimental, translational, clinical, and applied research.
Motivating national and international collaboration is one of the central aims of our working group. We have initiated two international multicontinental consortia that perform exciting research on cardiovascular imaging in patients with suspected coronary artery disease (COME-CCT) and patients who already have coronary stents (COME-CSI).
Very recently, Marc Dewey’s working group received an EU Framework grant for the DISCHARGE project. This group of 30 academic partners from 18 countries is coordinated by Marc Dewey and will allow the investigators to raise awareness among patients, health care providers, and decision-makers about the effectiveness and cost-effectiveness of coronary CT angiography.
Please find a comprehensive list of our publications in Pubmed here.