Funding in the DFG priority programme Radiomics
Over the next three years, the DFG will provide eight million euros to fund a priority programme on radiomics with a total of 17 projects. The working group Prof. Dewey has successfully acquired two of these projects and will carry out new analyses of coronary plaques and coronary flow with data from over 3500 patients from the DISCHARGE study (www.dischargetrial.eu).
Feature in Radiology Podcast
The most recent publication by our dear AG members Maria Bosserdt, Elke Zimmermann and others entitled “Kidney Injury after Intravenous versus Intra-arterial Contrast Agent in Patients Suspected of Having Coronary Artery Diseas” has found its way into the RADIOLOGY podcast.
The podcast: Feel free to listen here (From minute 17:11 on).
The transcript: can be found here (At page 3).
More Radiology podcasts can be found here.
We would like to thank the editorial board of RADIOLOGY for featuring our work!
Charité Cardiac CT Course
Even Aunt Minnie recommends it! The Charité Universitätsmedizin Berlin radiology department is hosting a hands-on cardiac CT course (www.ct-kurs.de) from 16. to 20. September, and a limited number of spaces are still available.
About the course:
There have been dramatic technical advances in computed tomography for imaging of the heart and particularly the coronary arteries. During the course you will had 100 hands-on cardiac CT cases with invasive angiography correlation. Also, overview lectures on patient preparation and scanning, as well as image reconstruction and reading will be given. Also see this publication on improvement of skills and knowledge by a hands-on cardiac CT course: https://www.ncbi.nlm.nih.gov/pubmed/20084596
Tweet by AuntMinnieEurope:
— AuntMinnieEurope (@AuntMinnieEuro) September 5, 2019
“Wir sind sehr Stolz!”
Congratulations to the Berlin University Alliance which was selected after peer review and onsite evaluations by DFG and Wissenschaftsrat for funding in the Excellence Strategy Program on July 19.
Professor Dewey is supporting the Alliance as the Charité representative on the Steering Committee fostering knowledge exchange and in the research forums led by Professor Christine Ahrend from TU Berlin. A country-wide map of funding of the Excellence Strategy can be found here.
Let’s keep up the excellent work!
The Bionic Radiologist: avoiding blurry pictures and providing greater insights.
Prof. Dr. Marc Deweys and Uta Wilkens latest realease helps at a practical level to achieve the following critical goals: (1) testing decisions being made scientifically on the basis of disease probabilities and patient preferences; (2) image analysis done consistently at any time and at any site; and (3) treatment suggestions that are closely linked to imaging results and are seamlessly integrated with other information.
The Bionic Radiologists promises better outcomes and lower costs through better integration of diagnostic imaging in clinical care processes. In this perspective we outlined the characteristics and facilitating factors with respect to the technology development itself, the surrounding institutional conditions and resistance due to the required change in culture as well as the prerequisites for individual acceptance and adaptation.
The Bionic Radiologist will thus help avoiding missed care opportunities. Read more…
Kidney Injury after Intravenous versus Intra-arterial Contrast Agent in Patients Suspected of Having Coronary Artery Disease: A Randomized Trial
Eva Schönenberger, Peter Martus, Maria Bosserdt, Elke Zimmermann, Rudolf Tauber, Michael Laule and Prof. Marc Dewey teamed up to compare intravenous versus intra-arterial contrast agent administration in relationship to AKI and analyze the association between AKI and chronic kidney disease.
The results and conclusion:
A total of 320 participants (163 [50.9%] women; mean age, 60 years ± 11) were included. Baseline eGFR did not differ between the CT angiography group (84.3 mL/min/1.73 m2 ± 17.2) and the catheterization group (87.1 mL/min/1.73 m2 ± 16.7) (P = .14). AKI occurred in nine of 161 participants in the CT angiography group (5.6%; 95% CI: 3%, 10%) and in 21 of 159 participants in the catheterization group (13.2%; 95% CI: 9%,19%) (relative risk, 2.4; 95% CI: 1.1, 5.0; P = .02). Also in the subgroup of participants without obstructive CAD, in those not requiring coronary interventions, AKI was more common in the catheterization group (11.9%; 95% CI: 8%, 19%) than in the CT angiography group (4.3% [95% CI: 2%, 9%]; difference, 7.7% [95% CI: 1.3%, 14.1%]; relative risk, 2.8 [95% CI: 1.1, 7.0]; P = .02). Obstructive CAD (odds ratio [OR]: 2.7 [95% CI: 1.1, 6.6]; P = .02), femoral catheter access (OR: 2.5 [95% CI: 1.1, 5.6]; P = .04), and cine ventriculography were associated with AKI (OR: 2.3 [95% CI: 1.0, 4.9]; P = .03). In multivariable analysis, the presence of postcontrast AKI was associated with chronic kidney disease (hazard ratio: 12.4 [95% CI: 4.5, 34.6]; P < .01).
Acute kidney injury was more common after cardiac catheterization than after CT angiography in this prospective randomized study of patients suspected of having coronary artery disease.
Read about this release here.
Summer excursion to Prenzlauer Berg
The Dewey AG is not only researching the hottest topics of radiology, but we’re also curious explorers of our city and our neighbourhood of Prenzlauer Berg. The home district of Prof. Dewey was part of a guided summer excursion with many interesting and little known facts about this very historical part of Berlin.
It was a great saturday, we are looking forward to the next excursion!
The latest scientific release from Mr. Robert Haase by the british Medical Journal on the topic of “Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data”.
The objective was to determine whether coronary computed tomography angiography (CTA) should be performed in patients with any clinical probability of coronary artery disease (CAD), and whether the diagnostic performance differs between subgroups of patients. Read more about it here.
May 22, 2019
Prof. Dr. Udo Hoffmann, Professor of Radiology at Harvard Medical School and Chief of Cardiovascular Imaging at Massachusetts General Hospital (Boston, USA) has been selected in a new round of BIH visiting professor approvals. Together with the two hosts from the Radiology Department of the Charité, Professor Dr. Bernd Hamm and Professor Dr. Marc Dewey, their mutual aim is the preparation of an international research network for the joint use of imaging data (GUIDE-IT). We’d like to say congratulations and we’re eager to work with you!
About Prof. Dr. Hoffmann:
Udo is a pioneer and world leader in cardiovascular imaging. He leads a vibrant multidisciplinary research program at MGH focused on translational and clinical research to utilize cardiovascular imaging to improve prevention, diagnosis, and treatment of cardiovascular disease. Dr. Hoffmann has led hallmark randomized clinical trials in CV imaging, including ROMICAT I and II, PROMISE, and REPRIEVE. He published more than 500 peer reviewed manuscripts is among the top 1% cited researchers in his field. He received the SCCT Gold Medal in 2018.
Read more about the new funding rounds at the Informationsdienst der Wissenschaft here.
The Dewey AG Team was involved in the Discharge trial, coordinated by Prof. Dr. Marc Dewey. The Discharge trial is a collaborative multinational research project project which examines for which patients with suspected coronary artery disease based on stable chest pain, cardiac computed tomography (CT) or cardiac catheterisation is best suited. (Video in German language.)
May 21, 2019
A short teasing video from last years Pre-Research Forum with Prof. Dr. Marc Dewey being interviewed and asked about the upcoming questions of new health and artificial intelligence becoming a big part of radiology in the future.
May 9, 2019
The AG Dewey is officially back!
We are back in Berlin Mitte, inspired to drive things forward in todays medicine and radiology. The two days in the retreat held many informative speeches for the whole group and we are especially thankful to your guestspeakers who joined us in the last days. We would like to say thank you to Prof. Gabriel Krestin, Prof. Göran Bergström and Prof. Sebastian Stober, who were talking exciting topics such as artificial intelligence, shared their experiences with us and generally motivated enormously. And of course thanks to our Prof., Mr. Marc Dewey for making this event happen!
Take a brief look at the speeches of the team Dewey and our great guests:
April 27, 2019
The AG Dewey is officially retreating!
But only for a short time, to have some informative and inspiring days with
lectures, presentations and discussions from speakers of the AG Dewey as well as several guests. From Tuesday, 07.05.2019 until Wednesday, 08.05.2019 we will be residing in the Seminaris Hotel near Potsdam and are eager to hear about the most current and driving topics of radiology and the AG Dewey!
A rough overview about the topics of the presentations:
- Clinical Trials
- Artificial Intelligence
March 26, 2019
The following feels like a great compliment to all of our team, since we are always very eager to drive forward scientific research, medicine and technology here at the radiology department of the Charité in Berlin Mitte. The Charité has been mentioned within newsweek.com’s TOP 10 best hospitals in the world and Charité even makes it into their Top 5! Together with Statista Inc, a global market research and consumer data company, newsweek.com developed a groundbreaking ranking of the world’s best hospitals. Hospitals on this list are at the forefront of adapting to new challenges while providing top-notch patient care.
About the Charité Berlin newsweek.com states: “As a hospital, Charité—which celebrated its tricentennial in 2010—is on the cutting-edge of biomedical innovation, with biotech startup labs, advisory roles and business initiatives focused on the convergence of technology and medicine.”
Thank you for this compliment, we will keep giving our very best. Read the whole article by Noah Miller …
March 24, 2019
Prof. Dewey and the other group members congratulate Nader Aldoj on being awarded the best paper presentation of the “My Thesis in 3 Minutes” Session MY 7 at the ECR 2019.
March 22, 2019
A current publication under participation of the radiology department of Charité under Prof. Dr. Marc Dewey takes on “Patient Preferences for Coronary CT Angiography with Stress Perfusion, SPECT, or Invasive Coronary Angiography”.
In a multicenter prospective study, patients had a two- to threefold preference for coronary CT angiography with stress perfusion over SPECT and invasive coronary angiography for evaluation of coronary artery disease.
Read more about it here.
Also take a look at the paper about “preferences in cardiac testing” and the question “Why patient experience matters” from the Mallinckrodt Institute of Radiology by Pamela K. Woordward and Thuy D. Nguyen in this publication.
March 15, 2019
Interview of Prof. Dr. Marc Dewey by Michael Reiter on radiological studies at Universitätsmedizin Charité Berlin. Learn about the DISCHARGE study and much more about what is going on in the Charité radiology department in the video.
March 8, 2019
The project “Fractal Analysis of Myocardial Ischemia” of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) applied successfully for a Mercator-Fellow – the first ever in Radiology. Kakuya Kitagawa, MD, PhD, of the Department of Radiology at the Mie University Hospital in Japan will be supporting the project with his expertise and his international perspective.
The DFG-project “Fractal Analysis” was proposed by Prof. Dr. Marc Dewey and Dr. Florian Michallek from the department of Radiology at Charité Universitätsmedizin Berlin. The researchers want to develop a method to examine the causes of chronic ischaemic heart disease in a better and non-invasive way. They investigate if fractal analysis is a comprehensive perfusion analysis method (Figure 1). “We are looking forward to the scientific contribution of Kakuya to this project as he is one of the most renown experts on multimodality myocardial perfusion imaging worldwide.” says Prof. Dewey and Dr. Michallek explains “The Mercator-Fellowship Programme allows on the one hand to involve the distinguished expertise of Prof. Kitagawa for the project and on the other hand to synthesise a highly interesting and multi-centric dataset.
(From IDW-online press release)
February 27, 2019
The European Congress of Radiology (ECR) 2019 has just started in Vienna on February 27, 2019. We have seen great presentations in the sky-high stage (see picture), among them the publication by Dr. Bosserdt in Eur Radiol (link) about the ESR survey on imaging trials and data sharing. The group also enjoyed the small party at Henglbrunner (see picture).
January 30, 2019
Publication of “Impact and perceived value of journal reporting guidelines among Radiology authors and reviewers” in European Radiology by Marc Dewey, Deborah Levine, Herbert Y. Kressel and Marc Bossuyt.
September 28, 2018
This years BIOQIC best presentation award went to Nader Aldoj. Congratulations! .
September 26, 2018
Andreas Kofler and Nader Aldoj gave great presentations during todays BIOQIC day at Charité. We wish them success with their upcoming developments!.
August 1, 2018
Congratulations to Professor Peter Scholze for being awarded the Fields Medal. Heinrich Hertz School rocks.
June 15, 2018
Very successful playful learning lecture about imaging for 3rd semester medical students by Dr. Diekhoff and Prof. Dewey. We will continue this and include the iGUIDE tool of the ESR.
Mai 8, 2018
scct 2018 abstract acceptance celebration by the following team members, from the left, Christian Wald, Nader Aldoj, Sepher Zagaran, Andreas Kofler, Maria Bosserdt, Marc Dewey
April 23, 2018
Adriane Elisabeth Napp has successfully completed her disputation on 23 April 2018 with the topic “Claustrophobia during MRI” with magna cum laude.
She thanks the entire team and her thesis supervisor, Prof. Marc Dewey, for the exciting time and great support.
March 19, 2018
Today, European Radiology published the first multicenter analysis from the COME-CCT Consortium online. Investigators from 65 institutions participated in this study which analysed the applicability and accuracy of clinical probability calculations for coronary artery disease and their impact in guidelines. The study is first authored by Robert Röhle and Viktoria Wieske from our team (please see picture on the left). Congratulations!
March 2, 2018
Today, the third Clinical Trials in Radiology session at ECR 2018 took place. The first two Clinical Trials in Radiology sessions took place already the last two days at the new Sky High Stage in Vienna. The focus of the Clinical Trials in Radiology session today were again large clinical trials, this time highlighting two tomography breast cancer screening trials from Scandinavia both including more than 10,000 patients (Malmö and Bergen), a subanalysis of the MR Clean Trial, the NU-AGE trial, a large trial on dose reduction in CT called Partnership for Dose including more than 1 million examinations, and the long-term results of the AMACING trial. The session was strengthened by six discussants who provided their perspective on the clinical implications of the trials and was moderated by the immediate past president of the RSNA Professor Richard L. Ehman and Professor Marc Dewey (please see picture on the left).
March 1, 2018
Professor Marc Dewey has presented today the Honorary Wilhelm-Conrad Röntgen Lecture entitled ‘Value-based imaging: the future is now! at the European Congress of Radiology in Vienna and received his certificate of appreciation by the President of the congress and European Society of Radiology, Professor Bernd Hamm (please see picture on the left).
Radiology has published in its current issue the multicenter study by Drs. Rief and Chen from our group and the NIH about quantitative myocardial perfusion imaging. The study was featured by being on the cover of Radiology (please see picture on the left) and a special report by Auntminnie.com.
February 5, 2018
Today, Tobias Penzkofer successfully completed his ‘ öffentlich wissenschaftlichen ‘
Vortrag as part of his habilitation about image-guided interventions
Congratulations from the entire team
January 30, 2018
A new article written by Dr. Matthias Rief et al. has been published in European Radiology. It is about DNA double strands breaks in blood lympthocytes.
Please find a link to the article below:
January 24, 2018
Yesterday, four teams from the digital health accelerator and two start-ups from the Charite medical university have participated and presented their innovative ideas and solutions .
All the ideas were based on a variety of new methods such as new algorithms, sensor technology and big data analysis.
Prof. Marc Dewey (top picture) and Dr. Florian Michallek (bottom picture) have presented their digital health solutions in the Demo day organized by the Berlin Institute of Health (BIH).
For more information about the event, please check the link below.
January 5, 2018
We started the new year with a friendly dinner. the spirit was high and everyone from the group seems to be highly motivated to start the year and have a great time.
December 4, 2017
Our 3rd whole-week cardiac CT hands-on course started today with 20 participants. We are offering cardiac CT hands-on courses since more than a decade and have extended our concept which has been published after successful evaluation to full-week courses with 100 cases with catheterization correlation. We’ll have our 4th whole-week cardiac CT hands-on course from September 24 until 28, 2018. Please contact us asap as the places are booking fast.
November 29, 2017
The technical innovation team has attended an intensive deep learning course (CoSIP Intense Course on Deep Learning) organized by TUB. The course was very informative and well organized
November 24, 2017
Today, Elke Zimmermann finished her habilitation about cardiac CT. Congratulations from the entire team!
November 7, 2017
Dr. Sarah Feger (second from right), Keno Bressem (left), and Dr. Florian Michallek (second from left) and presented results from the Digital Health Accelerator initiative of the Berlin Institute of Health for the group of Professor Dewey (right) at the Future Medicine Congress. All three presenters from our team received ginger hearts for their presentation. Congratulations!
November 4, 2017
Professor Dewey presented the results about contrast-induced acute kidney injury after intravenous versus intraarterial contrast agent at the oral High-Impact Clinical Trials session at Kidney Week of the American Society of Nephrology today. First press releases about this session can be found here medscape about study from charité
October 2, 2017
Today we started the Digital Health Accelerator at the working group of Professor Dewey. This initiative is funded by the Berlin Institute of Health. Further information can be found in the press release. Three new team members joined us today for the Digital Health Accelerator: Dr. Christian Wald, Orhan Konak, and Sepher Zargaran. Welcome!
Congratulations to Malwina Kaniewska who completed her dissertation with magna cum laude on June the 12th 2017. Malwina Kaniewska thanks the whole team and her thesis supervisior, Prof. Marc Dewey for their support
Nader Aldoj and Andreas Kofler joined our research team as PhD students in the BIOQIC program. They will both be working on deep learning techniques for image analysis. Welcome to our team!
April 26, 2017
The First German TV branch RBB was the first TV station to broadcast a live cardiac CT examination. The full program of this edition of RBB Praxis can be found here. Most important time slots of the video in the media library of RBB are the introduction of the patient (at 5:19 min), the live CT scan (at 10:07 min), and the evaluation of cardiac CT results (at 33:16 min). The DISCHARGE trial can still include patients. Do not hesitate to contact us with any questions or suggestions!
March 14, 2017
RSNA News discusses the recent results of our study by Napp et al. on a pre-MRI questionnaire to help identify patients more likely to develop claustrophobia.
February 14, 2017
We will have our international speaker meeting on tracking and optimizing radiation dose for CT on March 6th, 2017 from 10 until 12 AM. The international speaker is Professor Rebecca Smith-Bindman, who will be giving talks about the Partnership for DOSE and the STONE trial. Please contact Christine Germershausen in case you are interested to attend.
February 7, 2017
Congratulations to Florian Michallek who completed his dissertation about fractal analysis of myocardial perfusion by MR imaging with summa cum laude.
January 2, 2017
The BIOQIC consortium recently started to search for PhD candidates. Please check the website and apply if highly interested in one of the 15 PhD projects.
The RSNA 2016 Essentials Talk Handout is available here.
High-quality supervision of doctoral candidates is pivotal also because of the potential of a European doctorate. Today, BMJ Open published the original research article of Elif Can on supervisors’ perspective on thesis projects. We believe that true scientific collaboration between doctoral candidates and their supervisors needs to be facilitated by medical faculties and graduate programmes.
Professor Marc Dewey was elected by the professors working at Charité to become a member of the Charité Faculty Council.
The Berlin Medical Journal reports in an editorial about the combination of personalised and evidence-based medicine in the DISCHARGE trial.
The BMJ published a comment by us and Professor J. Dodd from Dublin on the ICMJE proposal on data sharing.
Three members of our working group presented their research projects during the ECR 2016 in Vienna, March 2-6.
Dr. Sarah Feger presented her scientific work with focus on patient acceptance of coronary CT at two scientific cardiac sessions: “Patient satisfaction with coronary CT angiography, myocardial CT perfusion, myocardial perfusion MRI, SPECT myocardial perfusion imaging and conventional coronary angiography”, and “Acceptance of combined coronary CT angiography and myocardial CT perfusion versus conventional coronary angiography in patients with coronary stents“.
Dr. Gianluca de Rubeis and Viktoria Wieske presented their topics, “DISCHARGE trial pilot study: Image quality and protocol adherence results”, and “CoMe-CCT: CT angiography versus Agatston score for diagnosis of coronary artery disease”, respectively, during this year’s Clinical Trials in Radiology session.
Today we had our perspectives meeting on pre- and posttest probability estimation. Professor Harold Sox was our special guest and provided interesting insights from his perspective as the editor of the book Medical Decision Making (2nd edition, 2013).
Dr. Gianluca de Rubeis received the certificate for being the first doctoral graduate of the DISCHARGE project during the meeting in Budapest.
We will have our perspectives meeting of the working group on pre- and posttest probability estimation on February 22nd, 2016 from 9 AM until 2 PM. As a special guest, the former editor-in-chief of the Annals of Internal Medicine, Professor Harold Sox, will be joining us and give two talks during the meeting. Please contact Christine Germershausen in case you are interested to attend.
Today, Nature published a correspondence by Professor Dewey on research training and plans for a European medical doctorate. Please feel free to comment, discuss and share with colleagues.
Sarah Feger and Florian Michallek joined the research team as full time members.
Both have recently completed their medical studies with ‘very good’ in the final state exam and already published first authorship publications, see here and here.
Congratulations and welcome as full-time members of our research team!
Dr. Maria Bosserdt and Dr. Melanie Estrella joined our research team as full-time study assistants.
They will be working on the DISCHARGE project (www.dischargetrial.eu).
Welcome to our team!
Congratulations to Fabian Stenzel who completed his dissertation with magna cum laude on October the 9th 2015.
September 24th, 2015
Gianluca de Rubeis, who stayed with us with Erasmus funding, completed is degree at his home university, Sapienza, based on the great work he did with us. Congratulations!
August 2nd, 2015
We will have our next perspectives meeting on laboratory values to be analyzed as part of the CAD-Man study on September 14, 2015 from 9 AM until 2 PM in the Seminarraum Experimentelle Radiologie. Invited guests will be Dr. T. Keller from Frankfurt and Dr. R. Ziebig from Berlin.
July 1st, 2015
Sarah Fegers publication on patient satisfaction with different cardiac imaging tests has been published in the July issue of European Radiology. Congratulations!
28 May 2015 -Article about the DISCHARGE project
Heike E. Krüger-Brand from German Medical Journal (Deutsches Ärzteblatt) reported in a 1-page article about the DISCHARGE project and the upcoming study. Please find the full text to this publication (in German) below.
Congratulations to our colleague Ahmed Shaban on the new addition to his family.Heartfelt wishes for his little girl. Ahmed Shaban will be in a paternity leave for the next two weeks.
The Executive Board of the International Society for Strategic Studies in Radiology (IS3R, www.is3r.org) has unanimously and enthusiastically elected Professor Marc Dewey as a member of the society’s Young Leaders Club on April 28, 2015.
Sarah Fegers publication on iterative reconstruction for visualisation of coronary arteries has been accepted by PLoS ONE on March 30, 2015.
Robert Haase presented the methods of the DISCHARGE trial during the late-breaking clinical trials session of ECR 2015 in Vienna on March 4.
Marc Dewey has been selected by ECR 2017 President Paul Parizel to become a member of the Progamme Planning Committee on February 15, 2015.
The DISCHARGE annual meeting took place from February 11 until 13, 2015 in Berlin. Over 70 investigators from 19 countries gathered in Berlin to discuss the start of the DISCHARGE pragmatic randomized controlled trial as the core of this EU funded project.
Marc Dewey gave the highlight lecture on cardiac CT developments at the Deutsche Kardiodiagnostiktage on January 16, 2015.
Cardiac CT has been published in its second and almost entirely revised edition including chapters by over 40 authors by Springer on September 1, 2014.
Elke Zimmermann has been selected for a Rahel Hirsch research scholarship on August, 10, 2014.